So, I'm probably not going to talk too often on this blog about chemistry, but I have been feeling a little frustrated with my chemistry as of late. Just last week, I decided to go back to terminal epoxides as my test substrate, rather than disubstituted epoxides. To my surprise, somthing actually happened - new peaks in the GC trace! Although I probably don't have product yet, at least I have reactivity. It is quite depressing to run screens and screens, only to see marginal conversion to nothing. One screen with new peaks = greatly increased morale. And that is good.
New Total Syntheses
1 week ago